Cannabis, Health, Medical

What is the Entourage Effect & What Does it Have to Do with CBD?

Cannabis and CBD

There’s a reason doctors inquire extensively about any medication you’re taking before prescribing another one. This is because drugs (or more specifically, the chemical compounds in them) can interact to produce different effects. On the rare occasion that such chemical substances interact positively, there are marked benefits. This concept can apply to cannabinoids. Cannabidiol (CBD) is one such cannabinoid that can benefit from such an effect. When you purchase it from Smokepost CBD Dispensary, enquire about any such effects. This will ensure that you know what to expect.

What is the Entourage Effect?

The entourage effect is the supposed phenomenon whereby different chemical compounds while having varied chemical actions, work together toward a more beneficial effect when combined. When it comes to cannabinoids, proponents of this theory assert that consuming raw, unprocessed marijuana from the plant is more beneficial than consuming extracted cannabinoids on their own. Originally coined by researchers Mechoulam and Shimon Ben-Shabat, the entourage effect is now an acceptable theory as far as cannabinoid use is concerned. The gist of this theory is that drugs from botanical sources can be more effective than isolated components of the same plant.

What are the Different Compounds of the Cannabis Plant?

To appreciate the entourage effect, it’s crucial to understand the different chemical compounds present in a typical cannabis plant. These include:

i) Cannabinoids: There are dozens of these chemical compounds in existence but only two of them are of importance to researchers and users. These include cannabidiol (CBD) and tetrahydrocannabinol (THC). THC is the most well-known of the pair, being responsible for causing mind-bending effects or “highs.” CBD is also potent and responsible for numerous physiological effects without mind-altering capabilities. Both CBD and THC exert their effects by acting on the body’s endocannabinoid system– a network of specialized receptors spanning the brain and numerous other body tissues.

In addition to THC and CBD, other notable cannabinoids include cannabinol (CBN) and tetrahydrocannabivarin (THCV) although their quantities in a regular cannabis plant are negligible.

ii) Terpenes: Much like cannabinoids, terpenes are also produced by the cannabis plant’s trichome system. They’re oils with a distinctive fragrance, giving either a floral or peppery scent. Some terpenes include linalool, limonene, and caryophyllene. Linalool, for example, is said to help with pain and anxiety while limonene helps with depression.

Entourage Effect Involving CBD

CBD, when extracted from the cannabis plant, is used for a variety of therapies. Many individuals seek CBD in some form for the following issues;

-Pain relief: Many CBD consumers report improved pain management. CBD, as a cannabinoid, acts on the body to produce pain relief. The body produces chemical substances (endocannabinoids) that help to reduce pain. Endocannabinoids act on their target receptors to do this. CBD affects the activities of these receptors to increase pain relief.

Management of some cancer symptoms: Cancer sufferers often experience things like nausea, vomiting, and chronic pain. While this benefit still requires more studies, many CBD users suffering from cancer report improved symptoms after using CBD for some time.

Neuroprotective properties: CBD helps to improve neurological symptoms in some like multiple sclerosis (MS). In MS, one of the nasty manifestations is muscle spasticity. CBD consumption helps to reduce such symptoms.

These are some of the benefits CBD consumers enjoy. However, such benefits tend to be more pronounced when CBD consumption is combined with terpenes. It appears that terpenes help to support CBD effectiveness.

What About THC and Other Cannabinoids?

While research is still ongoing, there is evidence to suggest that CBD can help to negate some of the negative effects of THC consumption. THC primarily causes mind alteration, causing individuals to feel “high.” When combined, CBD helps to neutralize THC’s effects as far as mind alteration goes. A crucial factor here is their ratios.

At a CBD-to-THC ratio of 1:1, THC mind-bending efficacy is noticeably reduced. When the CBD quantity is increased to twice that of THC, the latter’s ability to induce a high is greatly reduced.

The entourage effect here appears to be CBD gradually tempering THC’s efficacy and ability to cause a high with increasing quantities.

Entourage Effect: The Sum Being Greater Than the Individual Parts

Do cannabinoids, terpenes, and other constituent substances of cannabis work together to enhance one another’s effects, producing benefits that would otherwise not exist if they were working together—the entourage effect? Many scientists believe so while others demand more research to support such assertions.

Ultimately, if the entourage effect contributes even a tiny bit of effectiveness, CBD users won’t care much about more research.


More on this topic:

The Many Benefits of Cannabis: From Pain Relief to Neurological Disorders

The Many Benefits of Cannabis: From Pain Relief to Neurological Disorders

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